Introduction. Today, it is necessary to systematically apply pedagogical techniques and techniques for correcting the level of anxiety, especially with the use of creative interdisciplinary cooperation. Purpose of the research: to study the influence of actualization of creative interdisciplinary cooperation of chemistry and biology in biology lessons in 10 grades on the level of anxiety of students.

Materials and methods. The analysis of scientific literature was carried out, the quality of assimilation of the acquired knowledge was analyzed, and with the help of the observation program, the analysis of the influence of the quality of assimilation of new knowledge on the external manifestations of anxiety in the subjects was carried out. The study was carried out using the textbooks of V.V. Pasechnik in biology and O.S. Gabrielyan in chemistry. The reliability of the results was checked using the Student's test.

Results. The average score for performing independent work in the experimental class is higher than in the control; according to observation cards, the distribution of students with manifestations of an increased level of anxiety in the control class was revealed.

Discussion. The results are consistent with the findings of other researchers that the development of creative interdisciplinary cooperation helps to implement technologies of self-management of behavior and feelings, reduce stress and increase self-esteem.

Conclusion. The actualization of creative interdisciplinary cooperation of chemistry and biology in biology lessons affects the quality of the knowledge acquired by students, which, in turn, affects the external manifestations of an increased level of anxiety in them. With a better assimilation of educational material, manifestations of a high level of anxiety are less pronounced.

It was revealed that the actualization of creative interdisciplinary cooperation affects the external manifestations of an increased level of anxiety in students;

The used method of observing the external manifestations of anxiety among students in the classroom helped to form an idea of its changes;

The developed Observation Program meets the classical requirements (contains the purpose, object and subject of observation, the observation situation, their number and duration, a list of indicators).

1. Henker B., Whalen C.K., Jamner L.D. & Delfino R.J. (2002), “Anxiety, Affect, and Activity in Teenagers: Monitoring Daily Life With Electronic Diaries”, Journal of the American Academy of Child & Adolescent Psychiatry, vol. 41, no. 6, pp. 660–670. DOI: 10.1097/00004583-200206000-00005.

2. Lynch H., McDonagh C. & Hennessy E. (2021), “Social Anxiety and Depression Stigma Among Adolescents”, Journal of Affective Disorders, vol. 281, pp. 744-750. DOI: 10.1016/j.jad.2020.11.073.

3. Garcia I., O’Neil J. (2021), “Anxiety in Adolescent”, The Journal for Nurse Practitioners, vol. 17, no. 1, pp. 49–53. DOI: 10.1016/j.nurpra.2020.08.021/.

4. Yap M. B.H., Pilkington P.D., Ryan S.M., Kellycd C.M. & Jormab A.F. (2014), “Parenting strategies for reducing the risk of adolescent depression and anxiety disorders: A Delphi consensus study”, Journal of Affective Disorders, vol. 156, pp. 67–75. DOI: 10.1016/j.jad.2013.11.017.

5. Chiu K., Clark D.M. & Leigh E. (2021), “Cognitive predictors of adolescent social anxiety”, Behaviour Research and Therapy, vol. 137: 103801. DOI: 10.1016/j.brat.2020.103801.

6. Anderson P.D. & Tarshis T.P. (2018), “Technology: Friend or Foe for Teenagers With Anxiety and Depression?”, Journal of the American Academy of Child & Adolescent Psychiatry, vol. 57, no. 10: S251. DOI: 10.1016/j.jaac.2018.09.369.

7. Alfonso S.V. & Lonigan C.J. (2021), “Trait anxiety and adolescent's academic achievement: The role of executive function”, Learning and Individual Differences, vol. 85: 101941. DOI: 10.1016/j.lindif.2020.101941.

8. Corr R. & Pelletier-Baldelli P-B. (2021), “Neural mechanisms of acute stress and trait anxiety in adolescents”, NeuroImage: Clinical, vol. 29: 102543. DOI: 10.1016/j.nicl.2020.102543.

9. Khmelarova Z., Chonkova A. & Sholtes E. (2018), Strakh publichnykh vystupleniy u uchenikov i studentov v podrostkovom i yunosheskom vozraste [Fear of public speaking among pupils and students in adolescence and youth], Psikhologicheskaya nauka i obrazovaniye, 4 (23), 70–79. DOI: 10.17759 / pse.2018230407. (In Russian).

10. Fatikhova L.F. & Sayfutdiyarova E.F. (2020), Roditel'skaya otsenka kachestv bezopasnogo povedeniya lichnosti detey mladshego shkol'nogo, podrostkovogo i yunosheskogo vozrasta [Parental assessment of the qualities of safe behavior of the personality of children of primary school, adolescence and youth], Psikhologicheskaya nauka i obrazovaniye, 2 (25), 59–71. DOI: 10.17759 / pse.2020250205. (In Russian).

11. Kuzmina M.V. (2019), Svyaz' samootsenki i urovnya lichnostnoy trevozhnosti v podrostkovom vozraste [The relationship between self-esteem and the level of personal anxiety in adolescence], Nauchnyy poisk, 3 (1), 25–28. (In Russian).

12. Moirano, R., Sanchez, M.A. & Shtepanek, L. (2020), “Creative interdisciplinary collaboration: A systematic literature review”, Thinking Skills and Creativity, vol. 35: 100626. DOI: 10.1016/j.tsc.2019.100626.

13. Clare Kelly & Redmond O'Connell (2020), “Can Neuroscience Change the Way We View Morality?”, Neuron, no. 108(4), vol. 25, pp. 604–607. DOI: 10.1016/j.neuron.2020.10.024.

14. He J., Chen X. & Huang F. (2019), “Is there a relationship between body mass index and academic achievement? A meta-analysis”, Public Health, vol. 167, pp. 111–124. DOI: 10.1016/j.puhe.2018.11.002.

15. Bertie L.A., Sicouri G. & Hudson J.L. (2020), “Anxiety Disorders in Children and Adolescents”,Reference Module in Neuroscience and Biobehavioral Psychology. DOI: 10.1016/B978-0-12-818697-8.00040-6.

16. Bilsky S. A. & Friedman H. P. (2020), “The interaction between sleep disturbances and anxiety sensitivity in relation to adolescent anger responses to parent adolescent conflict”, Journal of Adolescence, vol. 84, pp. 69–77. DOI: 10.1016/j.adolescence.2020.08.005.

17. Vlasova G.I., Turchin A.S. (2019), Osobennosti trevozhnosti sovremennykh podrostkov-shkol'nikov [Features of anxiety in modern adolescent schoolchildren], Nauchnoye mneniye, 9, 16–21. (In Russian).

18. Imedadze I.V. (2019), Voprosy vozrastnoy i pedagogicheskoy psikhologii: L.S. Vygotskiy i D.N. Uznadze [Issues of developmental and educational psychology: L.S. Vygotsky and D.N. Uznadze], Kul'turno-istoricheskaya psikhologiya, 15 (2), 4–13. DOI: 10.17759 / ch2019150201. (In Russian).

19. Arzykulova A.T. & Alymbaeva E.A. (2018), Korrektsiya urovnya trevozhnosti podrostkov sredstvami art-terapii [Correction of the level of anxiety in adolescents by means of art therapy], Vestnik Bishkekskogo gumanitarnogo universiteta, 2, 106–108. (In Russian).

20. Sorochinsky M.A. (2017), Psikhologo-pedagogicheskiye osobennosti ispol'zovaniya elektronnogo obucheniya [Psychological and pedagogical features of the use of e-learning], Kontsept, 6, 274-278. (In Russian).

21. Stepanova V.V. & Tolstykh N.N. (2016), Mezhdistsiplinarnyye svyazi sotsial'noy, vozrastnoy i pedagogicheskoy psikhologii: resursy razvitiya [Interdisciplinary connections of social, developmental and educational psychology: development resources], Sotsial'naya psikhologiya i obshchestvo, 7(1), 23–44. DOI: 10.17759/sps.2016070103. (In Russian).